Ive got the american with the 12" base and wheels. ive never had an issue with or without the wheels. I shoot a lot on the beach and like rolling the stand across the piers or parking lots and then pulling it right out of the wheels and plopping it into the sand. but everyones got their own methods. i put all three wheels and the utility tray and my docking bracket into one milk crate, along with some extra ratchet straps etc. for travel in the truck.
also, i have the two-riser version and I wish i had the single rise, but if you are doing any superpost work at all, then the two riser is probably a must. and the two-riser is probably much better for the jumbos girls.
while i love the stand, i had a gnarly experience with american. it took over two months for them to build the stand (as they didnt have them in stock), constant communication issues, and i had ordered the single riser version but they built and charged me for the double-riser. i did not find phil easy to work with until i showed up at the factory to pick up the stand and i was writing the check.
also, i suggest wrapping the knobs in a buffer/rubber coating of sorts to avoid any bumping with your rig. i just used some long gear ties and wrapped them around the knobs to buffer any knocking around, which happens from time to time. just trying to keep everything in good shape. you can see them in orange in the photo.